CHEMICAL
COMPOSITION Guggul resin contains a number of
compounds- a diterpene hydrocarbon, a diterpene alcohol, Z-gugulsterone, E-gugulsterone,guggulsterol-I,
Guggulsterol-II, guggulsterol-III 1.
PHARMACOLOGY The
two main areas of investigation have been its hypolipidaemic
action, which has been recognised since the vedic ages and its
antiinflammatory effect. Oral administration of guggul produce
lower cholesterol levels and lessening in serum turbidity2 .The cholesterol
lowering effects have been seen in monkeys kept on a high cholesterol
diet, the results being comparable to those of Atromid-S 3. it
has a high antiinflammatory potential against Brownlee's formaldehyde
induced arthritis in albino rats4.